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Case Series of the Management of Surgical Site Infection Following Thoracic Spinal Surgeries During COVID Pandemic

Volume 3 | Issue 1 | April-September 2022 | page: 24-31 | Neetin Mahajan, Sunny Sangma, Jayesh Mhatre, Pritam Talukder

DOI: https://doi.org/10.13107/bbj.2022.v03i01.036


Authors: Neetin Mahajan [1], Sunny Sangma [1], Jayesh Mhatre [1], Pritam Talukder [1]

[1] Department of Orthopaedics, Grant Government Medical College, Mumbai, Maharashtra, India.

Address of Correspondence

Dr. Sunny Sangma,
Department of Orthopaedics, Grant Government Medical College, Mumbai, Maharashtra, India.
E-mail: Sunnysangma11@gmail.com


Abstract


Introduction: Post-operative spinal wound infection increases the morbidity of the patient and the cost of healthcare. Despite the development of prophylactic antibiotics and advances in surgical technique and post-operative care, wound infection continues to compromise patient outcome after spinal surgery. This kind of infection places the patient at risk for pseudoarthrosis, adverse neurologic sequelae, chronic pain, deformity, and even death. In spite of all preventive measures, the SSI following spinal surgeries are 1% among operated spinal instrumentation.
Case Series: Here, we present a series of three patients who presented to us with post-operative surgical site infection (SSI) in spine surgery in the form of wound, discharge, and other complaints. Out of all, two of them were operated with debridement and skin closure followed by broad spectrum IV antibiotics and one of them managed with vacuum-assisted closure dressing and high antibiotics sensitive to organisms found in wound culture. Optimization by building up hemoglobin, supplementing micronutrients including Vitamin C, D, and B12 and high protein diet was started as adjuvant therapy and all of them was discharged with healthy wound.
Conclusion: SSI in spine surgery is a common but challenging complication, particularly after instrumental spinal arthrodesis. Using meticulous aseptic technique, intra-operative irrigation, prophylactic antibiotics, and optimizing patient factors preoperatively are key to preventing a SSI. In patients who still develop an infection despite efforts at prevention, timely diagnosis and treatment are critical. Instrumentation can be retained while still successfully clearing an early infection, although following fusion, instrumentation can be removed if lifetime oral antibiotic suppression is either not indicated or undesirable.
Keywords: Spine surgery, Postoperative infections, Surgical site infection, Spinal instrumentation.


References


1. Massie JB, Heller JG, Abitbol JJ, McPherson D, Garfin SR. Postoperative posterior spinal wound infections. Clin OrthopRelat Res 1992;284:99-108.
2. Sasso RC, Garrido BJ. Postoperative spinal wound infections. J Am Acad Orthop Surg 2008;16:330-7.
3. Weinstein MA, McCabe JP, Cammisa FP Jr. Postoperative spinal wound infection: A review of 2,391 consecutive index procedures. J Spinal Disord 2000;13:422-6.
4. Picada R, Winter RB, Lonstein JE, Denis F, Pinto MR, Smith MD, et al. Postoperative deep wound infection in adults after posterior lumbosacral spine fusion with instrumentation: Incidence and management. J Spinal Disord 2000;13:42-5.
5. Ido K, Shimizu K, Nakayama Y, Shikata J, Matsushita M, Nakamura T. Suction/irritation for deep wound infection after spinal instrumentation: A case study. Eur Spine J 1996;5:345-9.
6. Viola RW, King HA, Adler SM, Wilson CB. Delayed infection after elective spinal instrumentation and fusion. A retrospective analysis of eight cases. Spine 1997;22:2444-51.
7. Gristina AG, Costerton JW. Bacterial adherence to biomaterials and tissue. The significance of its role in clinical sepsis. J Bone Joint Surg Am 1985;67:264-73.
8. Richards B. Delayed infections following posterior spinal instrumentation for the treatment of isopathic scoliosis. J Bone Joint Surg Am 1995;77:524-9.
9. Dietz FR, Koontz FP, Round EM, Marsh JL. Thee importance of positive bacterial cultures of specimens obtained during clean orthopaedic operations. J Bone Joint Surg Am 1991;73:1200-7.
10. Heggeness MH, Esses SI, Errico T, Yuan HA. Late infection of spinal instrumentation by hematogenous seeding. Spine 1993;18:492-6.
11. Dubousset J, Shufflebarger H, Wenger D. Late “infection” with CD instrumentation. Orthop Trans 1994;18:121.
12. Robertson PA, Taylor TK. Late presentation of infection as a complication of Dwyer anterior spinal instrumentation. J Spinal Disord 1993;6:256-9.
13. Clark CE, Shufflebarger HL. Late-developing infection in instrumented idiopathic scoliosis. Spine 1999;24:1909-12.
14. Richards BS, Emara KM. Delayed infections after posterior TSRH spinal instrumentation for idiopathic scoliosis. Spine 2001;18:1990-6.
15. Hatch RS, Sturm PF, Wellborn CC. Late complication after single rod instrumentation. Spine 1998;13:1503-5.
16. Wimmer C, Gluch H. Aseptic loosening after CD instrumentation in the treatment of scoliosis: A report about eight cases. J Spinal Disord 1998;11:440-3.
17. Rigamonti D, Liem L, Sampath P, Knoller N, Namaguchi Y, Schreibman DL, et al. Spinal epidural abscess: Contemporary trends in etiology, evaluation, and management. Surg Neurol 1999;52:189-97.
18. Post MJ, Sze G, Quencer RM, Eismont FJ, Green BA, Gahbauer H. Gadolinium-enhanced MR in spinal infection. J Comput Assist Tomogr1990;14:721-9.
19. Smith AS, Blaser SI. Infectious and inflammatory processes of the spine. Radiol Clin North Am 1991;29:809-27.
20. Thalgott JS, Cotler HB, Sasso RC, LaRocca H, Gardner V. Postoperative infections in spinal implants. Classification and analysis: A multicenter study. Spine (Phila Pa 1976) 1991;16:981-4.
21. Mehbod AA, Ogilvie JW, Pinto MR, Schwender JD, Transfeldt EE, Wood KB, et al. Postoperative deep wound infections in adults after spinal fusion: Management with vacuum-assisted wound closure. J Spinal Disord Tech 2005;18:14-7.
22. Dumanian GA, Ondra SL, Liu J, Schafer MF, Chao JD. Muscle flap salvage of spine wounds with soft tissue defects or infection. Spine 2003;28:1203-11.
23. Mitra A, Mitra A, Harlin S. Treatment of massive thoracolumbar wounds and vertebral osteomyelitis following scoliosis surgery. Plast Reconstr Surg 2004;113:206-13.
24. Yuan-Innes MJ, Temple CL, Lacey MS. Vacuum-assisted wound closure: A new approach to spinal wounds with exposed hardware. Spine 2001;26:E30-3.


How to Cite this Article: Mahajan N, Sangma S, Mhatre J, Talukder P | Case Series of the Management of Surgical Site Infection Following Thoracic Spinal Surgeries During COVID Pandemic | Back Bone: The Spine Journal | April-September 2022; 3(1): 24-31.    https://doi.org/10.13107/bbj.2022.v03i01.036

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Spine Surgery: A Narrative Review About Recent Updates and Future Directions

Volume 3 | Issue 1 | April-September 2022 | page: 07-13 | Nandan A. Marathe, Pauras P. Mhatre, Sudeep Date, Ayush Sharma
DOI: https://doi.org/10.13107/bbj.2022.v03i01.033


Authors: Nandan A. Marathe [1], Pauras P. Mhatre [1], Sudeep Date [2], Ayush Sharma [3]

[1] Department of Orthopaedics, Seth G.S. Medical College & KEM Hospital, Mumbai, Maharashtra, India.
[2] Department of Orthopaedics, Cumberland Infirmary, Newtown Road, Carlisle CA2 7HY, United Kingdom.
[3] Consultant Spine Surgeon and Head of Spine unit, Railway Hospital, Mumbai, Maharashtra, India.

Address of Correspondence
Pauras P. Mhatre,
Seth G.S. Medical College & KEM Hospital, Mumbai, India.
E-mail: paurasmhatre@gmail.com


Abstract


Background: Advances in case selection, operative methods, and postsurgical care have facilitated spine surgeons to manage complex spine cases with short operative times, decreased hospital stay and improved outcomes.
Methods: This is an overview of recent updates and future directions in the field of spine surgery. All the articles were obtained through a literature review on PubMed.
Results: Minimally invasive spine procedures like Endoscopic spine surgeries, Oblique Lumbar Interbody Fusion, use of retractor systems, etc. are emerging in rapidly in modern world. Fusion surgeries are associated with adjacent level disease hence, motion preservation surgeries that mimic the natural biomechanics of the spine are being explored as alternatives. In view of risks to vital structures, nerve injury due to mal-positioning, etc.; robotic spine surgery has paved a way to allow surgeons real-time procedural manipulation along with instrument control, real-scale magnification. Many high-impact discoveries in cancer research, stereotactic radiotherapy, newer combinations of chemotherapy, and tumor-specific antibodies have increased our understanding of spine oncology. Past two decades have seen many advancements in treatment of spine deformities right from initial radiographic assessment, surgical planning to postoperative care.
Conclusion: All in all, all stakeholders in innovation including the industry, scientists and surgeons must work in an open and honest collaboration to benefit the future patients and continue the evolution in Spine Surgery.
Keywords: Spine surgery, Recent updates, Minimally invasive surgery, Artificial disc replacement, Artificial intelligence.


References


[1] Kazemi N, Crew LK, Tredway TL. The future of spine surgery: New horizons in the treatment of spinal disorders. Surg Neurol Int 2013;4:15–21. doi:10.4103/2152-7806.109186.
[2] Fehlings MG, Ahuja CS, Mroz T, Hsu W, Harrop J. Future advances in spine surgery: The AOSpine North America perspective. Clin Neurosurg 2017;80:S1–8. doi:10.1093/neuros/nyw112.
[3] Perez-Cruet MJ, Foley KT, Isaacs RE, Rice-Wyllie L, Wellington R, Smith MM, et al. Microendoscopic lumbar discectomy: technical note. Neurosurgery 2002;51:S129-36.
[4] Guiot BH, Khoo LT, Fessler RG. A minimally invasive technique for decompression of the lumbar spine. Spine (Phila Pa 1976) 2002;27:432–8. doi:10.1097/00007632-200202150-00021.
[5] O’Toole JE, Eichholz KM, Fessler RG. Minimally invasive insertion of syringosubarachnoid shunt for posttraumatic syringomyelia: Technical case report. Neurosurgery 2007;61:E331-2; discussion E332. doi:10.1227/01.neu.0000303990.03235.81.
[6] Ogden AT, Fessler RG. Minimally invasive resection of intramedullary ependymoma: Case report. Neurosurgery 2009;65:E1203-4; discussion E1204. doi:10.1227/01.NEU.0000360153.65238.F0.
[7] Tredway TL, Musleh W, Christie SD, Khavkin Y, Fessler RG, Curry DJ. A novel minimally invasive technique for spinal cord untethering. Neurosurgery 2007;60:ONS70-4; discussion ONS74. doi:10.1227/01.NEU.0000249254.63546.D7.
[8] Tredway TL, Santiago P, Hrubes MR, Song JK, Christie SD, Fessler RG. Minimally invasive resection of intradural-extramedullary spinal neoplasms. Neurosurgery 2006;58:ONS52-8; discussion ONS52-8. doi:10.1227/01.neu.0000192661.08192.1c.
[9] Sandhu FA, Santiago P, Fessler RG, Palmer S. Minimally invasive surgical treatment of lumbar synovial cysts. Neurosurgery 2004;54:107–11; discussion 111-2. doi:10.1227/01.neu.0000097269.79994.2f.
[10] Karikari IO, Isaacs RE. Minimally invasive transforaminal lumbar interbody fusion: A review of techniques and outcomes. Spine (Phila Pa 1976) 2010;35:S294-301. doi:10.1097/BRS.0b013e3182022ddc.
[11] Ozgur BM, Yoo K, Rodriguez G, Taylor WR. Minimally-invasive technique for transforaminal lumbar interbody fusion (TLIF). Eur Spine J 2005;14:887–94. doi:10.1007/s00586-005-0941-3.
[12] Kulkarni AG, Kantharajanna SB, Dhruv AN. The use of tubular retractors for translaminar discectomy for cranially and caudally extruded discs. Indian J Orthop 2018;52:328–33. doi:10.4103/ortho.IJOrtho_364_16.
[13] Ozgur BM, Aryan HE, Pimenta L, Taylor WR. Extreme Lateral Interbody Fusion (XLIF): a novel surgical technique for anterior lumbar interbody fusion. Spine J 2006;6:435–43. doi:10.1016/j.spinee.2005.08.012.
[14] Isaacs RE, Hyde J, Goodrich JA, Rodgers WB, Phillips FM. A prospective, nonrandomized, multicenter evaluation of extreme lateral interbody fusion for the treatment of adult degenerative scoliosis: Perioperative outcomes and complications. Spine (Phila Pa 1976) 2010;35:S322-30. doi:10.1097/BRS.0b013e3182022e04.
[15] Hsieh PC, Koski TR, Sciubba DM, Moller DJ, O’Shaughnessy BA, Li KW, et al. Maximizing the potential of minimally invasive spine surgery in complex spinal disorders. Neurosurg Focus 2008;25:E19. doi:10.3171/FOC/2008/25/8/E19.
[16] Tormenti MJ, Maserati MB, Bonfield CM, Okonkwo DO, Kanter AS. Complications and radiographic correction in adult scoliosis following combined transpsoas extreme lateral interbody fusion and posterior pedicle screw instrumentation. Neurosurg Focus 2010;28:1–7. doi:10.3171/2010.1.FOCUS09263.
[17] Pimenta L, Oliveira L, Schaffa T, Coutinho E, Marchi L. Lumbar total disc replacement from an extreme lateral approach: Clinical experience with a minimum of 2 years’ follow-up: Clinical article. J Neurosurg Spine 2011;14:38–45. doi:10.3171/2010.9.SPINE09865.
[18] Jin C, Jaiswal MS, Jeun SS, Ryu KS, Hur JW, Kim JS. Outcomes of oblique lateral interbody fusion for degenerative lumbar disease in patients under or over 65years of age. J Orthop Surg Res 2018;13:1–10. doi:10.1186/s13018-018-0740-2.
[19] Yue JJ, Long W. Full endoscopic spinal surgery techniques: Advancements, indications, and outcomes. Int J Spine Surg 2015;9. doi:10.14444/2017.
[20] Blumenthal S, McAfee PC, Guyer RD, Hochschuler SH, Geisler FH, Holt RT, et al. A prospective, randomized, multicenter Food and Drug Administration Investigational Device Exemptions study of lumbar total disc replacement with the CHARITÉTM artificial disc versus lumbar fusion – Part I: Evaluation of clinical outcomes. Spine (Phila Pa 1976) 2005;30:1565–75. doi:10.1097/01.brs.0000170587.32676.0e.
[21] Guyer RD, McAfee PC, Hochschuler SH, Blumenthal SL, Fedder IL, Ohnmeiss DD, et al. Prospective randomized study of the Charité artificial disc: Data from two investigational centers. Spine J 2004;4:S252–9. doi:10.1016/j.spinee.2004.07.019.
[22] Geisler FH. The CHARITE Artificial Disc: design history, FDA IDE study results, and surgical technique. Clin Neurosurg 2006;53:223–8.
[23] Delamarter RB, Bae HW, Pradhan BB. Clinical results of ProDisc-II lumbar total disc replacement: Report from the United States clinical trial. Orthop Clin North Am 2005;36:301–13. doi:10.1016/j.ocl.2005.03.004.
[24] Sekhon LHS, Duggal N, Lynch JJ, Haid RW, Heller JG, Riew KD, et al. Magnetic resonance imaging clarity of the Bryan®, Prodisc-C®, Prestige LP®, and PCM® cervical arthroplasty devices. Spine (Phila Pa 1976) 2007;32:673–80. doi:10.1097/01.brs.0000257547.17822.14.
[25] Oskouian RJ, Whitehill R, Samii A, Shaffrey ME, Johnson JP, Shaffrey CI. The future of spinal arthroplasty: a biomaterial perspective. Neurosurg Focus 2004;17:E2. doi:10.3171/foc.2004.17.3.2.
[26] Robbins MM, Vaccaro AR, Madigan L. The use of bioabsorbable implants in spine surgery. Neurosurg Focus 2004;16:E1. doi:10.3171/foc.2004.16.3.2.
[27] Tafazal SI, Sell PJ. Incidental durotomy in lumbar spine surgery: Incidence and management. Eur Spine J 2005;14:287–90. doi:10.1007/s00586-004-0821-2.
[28] D’Andrea K, Dreyer J, Fahim DK. Utility of preoperative magnetic resonance imaging coregistered with intraoperative computed tomographic scan for the resection of complex tumors of the spine. World Neurosurg 2015;84:1804–15. doi:10.1016/j.wneu.2015.07.072.
[29] Gelalis ID, Paschos NK, Pakos EE, Politis AN, Arnaoutoglou CM, Karageorgos AC, et al. Accuracy of pedicle screw placement: A systematic review of prospective in vivo studies comparing free hand,fluoroscopy guidance and navigation techniques. Eur Spine J 2012;21:247–55. doi:10.1007/s00586-011-2011-3.
[30] Rampersaud YR, Lee KS. Fluoroscopic computer-assisted pedicle screw placement through a mature fusion mass: An assessment of 24 consecutive cases with independent analysis of computed tomography and clinical data. Spine (Phila Pa 1976) 2007;32:217–22. doi:10.1097/01.brs.0000251751.51936.3f.
[31] Roser F, Tatagiba M, Maier G. Spinal robotics: Current applications and future perspectives. Neurosurgery 2013;72:12–8. doi:10.1227/NEU.0b013e318270d02c.
[32] Overley SC, Cho SK, Mehta AI, Arnold PM. Navigation and Robotics in Spinal Surgery: Where Are We Now? Neurosurgery 2017;80:S86–99. doi:10.1093/neuros/nyw077.
[33] Lee JYK, Lega B, Bhowmick D, Newman JG, O’Malley BW, Weinstein GS, et al. Da vinci robot-assisted transoral odontoidectomy for basilar invagination. ORL 2010;72:91–5. doi:10.1159/000278256.
[34] Yang MS, Yoon DH, Kim KN, Kim H, Yang JW, Yi S, et al. Robot-assisted anterior lumbar interbody fusion in a swine model in vivo test of the da vinci surgical-assisted spinal surgery system. Spine (Phila Pa 1976) 2011;36:E139-43. doi:10.1097/BRS.0b013e3181d40ba3.
[35] Kim MJ, Ha Y, Yang MS, Yoon DH, Kim KN, Kim H, et al. Robot-assisted anterior lumbar interbody fusion (ALIF) using retroperitoneal approach. Acta Neurochir (Wien) 2010;152:675–9. doi:10.1007/s00701-009-0568-y.
[36] Ponnusamy K, Chewning S, Mohr C. Robotic approaches to the posterior spine. Spine (Phila Pa 1976) 2009;34:2104–9. doi:10.1097/BRS.0b013e3181b20212.
[37] Artibani W, Fracalanza S, Cavalleri S, Iafrate M, Aragona M, Novara G, et al. Learning curve and preliminary experience with da Vinci-assisted laparoscopic radical prostatectomy. Urol Int 2008;80:237–44. doi:10.1159/000127333.
[38] Holly LT, Foley KT. Intraoperative spinal navigation. Spine (Phila Pa 1976) 2003;28:S54-61. doi:10.1097/01.BRS.0000076899.78522.D9.
[39] Ughwanogho E, Patel NM, Baldwin KD, Sampson NR, Flynn JM. Computed tomography-guided navigation of thoracic pedicle screws for adolescent idiopathic scoliosis results in more accurate placement and less screw removal. Spine (Phila Pa 1976) 2012;37:E473-8. doi:10.1097/BRS.0b013e318238bbd9.
[40] Lee JH, Jang HL, Lee KM, Baek HR, Jin K, Hong KS, et al. In vitro and in vivo evaluation of the bioactivity of hydroxyapatite-coated polyetheretherketone biocomposites created by cold spray technology. Acta Biomater 2013;9:6177–87. doi:10.1016/j.actbio.2012.11.030.
[41] Schroeder GD, Hsu WK, Kepler CK, Kurd MF, Vaccaro AR, Patel AA, et al. Use of recombinant human bone morphogenetic protein-2 in the treatment of degenerative spondylolisthesis. Spine (Phila Pa 1976) 2016;41:445–9. doi:10.1097/BRS.0000000000001228.
[42] Zweckberger K, Ahuja CS, Liu Y, Wang J, Fehlings MG. Self-assembling peptides optimize the post-traumatic milieu and synergistically enhance the effects of neural stem cell therapy after cervical spinal cord injury. Acta Biomater 2016;42:77–89. doi:10.1016/j.actbio.2016.06.016.
[43] Leckie AE, Akens MK, Woodhouse KA, Yee AJM, Whyne CM. Evaluation of thiol-modified hyaluronan and elastin-like polypeptide composite augmentation in early-stage disc degeneration: Comparing 2 minimally invasive techniques. Spine (Phila Pa 1976) 2012;37:E1296-303. doi:10.1097/BRS.0b013e318266ecea.
[44] Leung VYL, Tam V, Chan D, Chan BP, Cheung KMC. Tissue Engineering for Intervertebral Disk Degeneration. Orthop Clin North Am 2011;42:575–83. doi:10.1016/j.ocl.2011.07.003.
[45] He Z, Zhai Q, Hu M, Cao C, Wang J, Yang H, et al. Bone cements for percutaneous vertebroplasty and balloon kyphoplasty: Current status and future developments. J Orthop Transl 2015;3:1–11. doi:10.1016/j.jot.2014.11.002.
[46] Girolami M, Boriani S, Bandiera S, Barbanti-Bródano G, Ghermandi R, Terzi S, et al. Biomimetic 3D-printed custom-made prosthesis for anterior column reconstruction in the thoracolumbar spine: a tailored option following en bloc resection for spinal tumors: Preliminary results on a case-series of 13 patients. Eur Spine J 2018;27:3073–83. doi:10.1007/s00586-018-5708-8.
[47] Smith JS, Shaffrey CI, Bess S, Shamji MF, Brodke D, Lenke LG, et al. Recent and Emerging Advances in Spinal Deformity. Neurosurgery 2017;80:S70–85. doi:10.1093/neuros/nyw048.
[48] Saindane AM. Recent Advances in Brain and Spine Imaging. Radiol Clin North Am 2015;53:477–96. doi:10.1016/j.rcl.2014.12.004.
[49] Mahboub-Ahari A, Hajebrahimi S, Yusefi M, Velayati A. EOS imaging versus current radiography: A health technology assessment study. Med J Islam Repub Iran 2016;30.


How to Cite this Article: Marathe NA, Mhatre PP, Date S, Sharma A | Spine Surgery: A Narrative Review About Recent Updates and Future Directions | Back Bone: The Spine Journal | April-September 2022; 3(1): 07-13. https://doi.org/10.13107/bbj.2022.v03i01.033

 


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Integrated Operation Theater Spine Suite (IOTSS) History of Spine Surgery: Lord Krishna the First Eternal Spine Surgeon

Volume 2 | Issue 2 | October 2021-March 2022 | page: 56-59 | Bharat R Dave
DOI: 10.13107/bbj.2022.v02i02.021


Authors: Bharat R Dave [1]

[1] Department of Spine Surgery, Stavya Spine Hospital & Research Institute, Ahmedabad, Gujarat, India.

Address of Correspondence
Dr. Bharat R Dave,
Consultant Spine Surgeon, Stavya Spine Hospital & Research Institute, Ahmedabad, Gujarat, India.
E-mail: Brd_172@yahoo.com


Abstract


The Mission has been to improve the quality of human life and do no harm. The significant change experienced during the training at England 1991 to 1996. Saga to be the best, be different and be unique continued. Necessary equipment installed like C Arm for fluoroscopy, radiolucent operation table and Anaesthesia machine. Safety increased due to optimisation of the operating room by implementation of available gadgets.
Many of us have witnessed the transition of an era, from handwritten Operation schedule call books to smartphone apps., from manual typewriters to high tech computers for research, from manual slide carousel to virtual presentations, from written high-risk consent to video consent and now from high radiation and lead aprons to Zero radiation exposure with O-Arm and navigation.
Integrated Operation Theatre Spine Suite– Enabling Technology – IOTSS is the latest version in optimising and additionally maximising the advantage of the surgery.
Keywords: Integrated spine suite, Optimizing results, Spine surgery


References


1. Brahmavaivarta Purana Sri-Krishna Janma Khanda (Fourth Canto) Chapter 72 English translation by Shantilal Nagar Parimal Publications. Available from: https://www.archive.org/details/brahma-vaivarta-purana-all-four-kandas-english-translation.
2. Bhishagratna K, Kaviraj KL. An English Translation of the Sushruta Samhita in Three Volumes. Vol. 1. Toronto: Archived by University of Toronto; 1907.
3. Carstensen K, Jensen EK, Madsen ML, Thomsen AM, Løvschall C, Dehbarez NT, et al. Implementation of integrated operating rooms: how much time is saved and how do medical staff experience the upgrading? A mixed-methods study in Denmark. BMJ Open 2020;10:e034459.
4. Gen ZT. Nikhil Raval. Available from: http://www.healthcaredesignmagazine.com/architecture/integrated-operating-room.


How to Cite this Article:  Dave BR Integrated Operation Theater Spine Suite | (IOTSS) History of Spine Surgery: Lord Krishna the First Eternal Spine Surgeon| Back Bone: The Spine Journal | October 2021-March 2022; 2(2): 56-59.

 


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SARS-CoV-2 (COVID-19) and Spine Surgeries in Tertiary-care Hospital of India

Volume 2 | Issue 1 | April-September 2021 | page: 23-26 | Bharat R. Dave, Ajay Krishnan, Ravi Ranjan Rai, Devanand Degulmadi, Shivanand Mayi, Kirit Jadhav


Authors: Ghanshyam Kakadiya [1], Kalpesh Saindane [1], Prashant Gedam [1], Nitin Pothare [1]

[1] Department of Orthopedics, TNMC & BYL Nair Hospital, Mumbai, Maharashtra, India.

Address of Correspondence
Dr. Ghanshyam Kakadiya,
Department of Orthopedics, TNMC & BYL Nair Hospital, Mumbai, Maharashtra, India.
E-mail: drghanshyam89@gmail.com


Abstract


The Coronavirus SARS-CoV-2 (COVID-19) pandemic has had a substantial effect on spine surgery worldwide. India, with its large population and limited health resources, will be overwrought due to the number of cases of critically ill patients with COVID-19. It is important to understand the challenges for spine surgeons in India when dealing with patients during the COVID-19 pandemic. In India, elective spine surgeries stand cancelled whilst trauma and emergency surgeries have been reorganised following Indian Orthopaedic Association and recent urgent British Orthopaedic association guidelines.
This article highlights the challenges in the triaging of patients, care in dealing with a patient with COVID-19 in spine surgery, and the effects on academics and research activities; it also suggests immediate measures and recommendations that also apply to other specialties.
Keywords: COVID-19, coronavirus disease, Spine surgery, India.


References


1. Jain AK. Current state of Orthopaedic education in India. Indian J Ortho,2016 C50: p.341–344.
2. https://www.boa.ac.uk/resources/covid-19-boasts-combined.html
3. https://www.rcseng.ac.uk/coronavirus/joint-guidance-for-surgeons/
4. https://www.cdc.gov/sars/guidance/i-infection/healthcare.pdf
5. Wong, KC, Leung, KS.(2004) Transmission and prevention of occupational infections in orthopaedic surgeons. J Bone Joint Surg Am. (86)1 : p.1065–1076.
6. Sandaradura, I, Goeman, E, Pontivivo, G (2020) A close shave? Performance of P2/N95 respirators in healthcare workers with facial hair: results of the BEARDS (BEnchmarking Adequate Respiratory DefenceS) study. J Hosp Infection (104) 4 : p.529-533
7. https://www.cdc.gov/niosh/npptl/pdfs/FacialHairWmask11282017-508.pdf
8. Jain, AK, Mukunth, R, Srivastava, A. (2015) Treatment of neglected femoral neck fracture. Indian J. (49)1: p.17–27
9. Liang ZC, Wang W, Murphy D. (2016) Novel coronavirus and orthopaedic surgery: early experiences from Singapore. Journal of Bone and Joint Surgery. 102(9): p.745-749
10. https://www.ioaindia.org/COVID-19IOAguidelines.pdf


How to Cite this Article:  Kakadiya G, Saindane K, Gedam P, Pothare N | SARS- CoV-2 (COVID-19) and Spine Surgeries in Tertiary-care Hospital of India | Back Bone: The Spine Journal | April-September 2021; 2(1):
23-26.

 


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Primary Ewing’s Sarcoma of Lumbar Spine Treated with Neoadjuvant Chemotherapy and Surgery – A Case Report

Volume 1 | Issue 1 | October 2020-March 2021 | page: 28-32 | Rohit A Thaker, Himanshu Dodiya, Shrikant Dhanani, Ankur Patel


Authors: Rohit A Thaker [1][2], Himanshu Dodiya [2], Shrikant Dhanani [2], Ankur Patel [3]

[1] Orthoplus Hospital, Spine Care Associates, Ahmedabad, Gujarat, India.
[2] Spine Care Associates, Ahmedabad, Gujarat, India.
[3] Sparsh Spine Hospital, Himmatnagar, Gujarat, India.

Address of Correspondence
Dr. Rohit A Thaker,
Consultat Spine Surgeon, Orthoplus Hospital, Spine Care Associates, Ahmedabad, Gujrat, India.
E-mail: thakerrohit1@gmail.com


Abstract


Primary involvement of mobile spine compared to non-mobile spine is very less in case of Ewing’s sarcoma (ES). There are no fixed guidelines for these types of tumors because of their low incidence. These tumors usually have very high sensitivity to chemotherapy and radiotherapy. Goal for the management of ES of the spine is adequate local control through complete removal of tumor by doing aggressive resection along with restoration of spinal stability and preservation of neurology. En bloc spondylectomy or extralesional resection with wide disease-free margin provides good oncological results with a longer survival. Whenever it is possible to give neoadjuvant chemotherapy, it is always better because it helps to shrink tumor, treat micrometastasis, and make surgical excision easier with wide margin resection. However, in some case of spinal ES, it may not be possible because of neurological compromise and they might have to be addressed first by surgery and neurological decompression. We report here one such cases of primary ES of mobile lumbar spine treated with neoadjuvant chemotherapy and then with en bloc excision of tumor. The clinical picture and imaging characteristics of patient were analyzed as well as the management modalities and outcome has been discussed.
Keywords: Ewing’s sarcoma, spine surgery, neoadjuvant chemotherapy, lumbar spine.

 


References

1. Berger M, Fagioli F, Abate M, Riccardi R, Prete A, Cozza R, et al. Unusual sites of Ewing Sarcoma (ES): A retrospective multicenter 30-year experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP) and Italian Sarcoma Group (ISG). Eur J Cancer 2013;49:3658-65.
2. Gupta AA, Pappo A, Saunders N, Hopyan S, Ferguson P, Wunder J, et al. Clinical outcome of children and adults with localized Ewing sarcoma: Impact of chemotherapy dose and timing of local therapy. Cancer 2010;116:3189-94.
3. Pilepich MV, Vietti TJ, Nesbit ME, Tefft M, Kissane J, Burgert O, et al. Ewing’s sarcoma of the vertebral column. Int J Radiat Oncol Biol Phys 1981;7:27-31.
4. Mirzaei L, Kaal SE, Schreuder HW, Bartels RH. The neurological compromised spine due to Ewing sarcoma. What first: Surgery or chemotherapy? Therapy, survival, and neurological outcome of 15 cases with primary Ewing sarcoma of the vertebral column. Neurosurgery 2015;77:718-24.
5. Marina NM, Pappo AS, Parham DM, Cain AM, Rao BN, Poquette CA, et al. Chemotherapy dose-intensification for pediatric patients with Ewing’s family of tumors and desmoplastic small round-cell tumors: A feasibility study at St. Jude Children’s Research Hospital. J Clin Oncol 1999;17:180-90.
6. Ferrari S, Palmerini E, Alberghini M, Staals E, Mercuri M, Barbieri E, et al. Vincristine, doxorubicin, cyclophosfamide, actinomycin D, ifosfamide, and etoposide in adult and pediatric patients with nonmetastatic Ewing sarcoma. Final results of a monoinstitutional study. Tumori 2010;96:213-8.
7. Gaspar N, Hawkins DS, Dirksen U, Lewis IJ, Ferrari S, Le Deley MC, et al. Ewing sarcoma: Current management and future approaches through collaboration. J Clin Oncol 2015;33:3036-46.
8. Gopalakrishnan CV, Shrivastava A, Easwer HV, Nair S. Primary Ewing’s sarcoma of the spine presenting as acute paraplegia. J Pediatr Neurosci 2012;7:64-6.
9. Vogin G, Helfre S, Glorion C, Mosseri V, Mascard E, Oberlin O, et al. Local control and sequelae in localised Ewing tumours of the spine: A French retrospective study. Eur J Cancer 2013;49:1314-23.
10. Papagelopoulos PJ, Currier BL, Galanis E, Grubb MJ, Pritchard DJ, Ebersold MJ. Vertebra plana caused by primary Ewing sarcoma: Case report and review of the literature. J Spinal Disord Tech 2002;15:252-7.
11. Erlemann R, Sciuk J, Bosse A, Ritter J, Kusnierz-Glaz CR. Response of osteosarcoma and Ewing sarcoma to preoperative chemotherapy: Assessment with dynamic and static MR imaging and skeletal scintigraphy. Radiology 1990;175:791-6.
12. Estes DN, Magill HL, Thompson EI, Hayes FA. Primary Ewing sarcoma: Follow-up with Ga-67 scintigraphy. Radiology 1990;177:449-53.
13. Schmidt D, Harms D, Pilon VA. Small-cell pediatric tumors: Histology, immunohistochemistry, and electron microscopy. Clin Lab Med 1987;7:63-89.
14. Venkateswaran L, Rodriguez-Galindo C, Merchant TE, Poquette CA, Rao BN, Pappo AS. Primary Ewing tumor of the vertebrae: Clinical characteristics, prognostic factors, and outcome. Med Pediatr Oncol 2001;37:30-5.
15. O’Phelan KH, Bunney EB, Weingart SD, Smith WS. Emergency neurological life support: Spinal cord compression (SCC). Neurocrit Care 2012;17:S96-101.
16. Boriani S, Amendola L, Corghi A, Cappuccio M, Bandiera S, Ferrari S, et al. Ewing’s sarcoma of the mobile spine. Eur Rev Med Pharmacol Sci 2011;15:831-9.
17. Subbiah V, Anderson P, Lazar AJ, Burdett E, Raymond K, Ludwig JA. Ewing’s sarcoma: Standard and experimental treatment options. Curr Treat Options Oncol 2009;10:126-40.
18. Zhang J, Huang Y, Lu J, He A, Zhou Y, Hu H, et al. Impact of first-line treatment on outcomes of Ewing sarcoma of the spine. Am J Cancer Res 2018;8:1262-72.
19. Arshi A, Sharim J, Park DY, Park HY, Yazdanshenas H, Bernthal NM, et al. Prognostic determinants and treatment outcomes analysis of osteosarcoma and Ewing sarcoma of the spine. Spine J 2017;17:645-55.
20. Uyeturk U, Helvaci K, Demirci A, Sonmez OU, Turker I, Afsar CU, et al. Clinical outcomes and prognostic factors of adult’s Ewing sarcoma family of tumors: Single center experience. Contemp Oncol (Pozn) 2016;20:141-6.


How to Cite this Article:  Thaker RA, Dodiya H, Dhanani S, Patel A| Primary Ewing’s Sarcoma of Lumbar Spine Treated with Neoadjuvant Chemotherapy and Surgery – A Case Report| Back Bone: The Spine Journal | October 2020-March 2021; 1(1): 28-32.

 


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