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Desflurane as an Effective Anaesthetic Agent for Intra-Operative Neuro-Monitoring in Spine Surgeries

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Volume 4 | Issue 1 | April 2023 – September 2023 | page: 20-23 | Meeta Agarwala, Hitesh N Modi, Deep J. Patel

DOI: https://doi.org/10.13107/bbj.20232.v04i01.055

Authors: Meeta Agarwala [1], Hitesh N Modi [1], Deep J. Patel [1]

[1] Department of Anaesthesia, Zydus Hospitals, Ahmedabad, Gujarat, India.
[2] Department of Spine Surgery, Zydus hospital, Ahmedabad, Gujarat, India.

Address of Correspondence

Dr. Meeta Agarwala,
Department of Anaesthesia, Zydus Hospitals, Ahmedabad, Gujarat, India.
E-mail: meetasomaiya@yahoo.com

Abstract

Background & Aims: Motor evoked potentials (MEP) have been widely used as intraoperative neuromonitoring in patients undergoing spine surgery to prevent neurological complications. The present study aims to show the significance of 6% desflurane as an effective agent in maintaining anaesthesia at a minimum alveolar concentration (MAC) of 0.8–1.0 in patients undergoing spine surgery with neuromonitoring.
Methods: This retrospective, cohort, single-centre study was conducted between 2016 and 2018. Patients who underwent spinal surgery along with intraoperative neuromonitoring were included. Anaesthesia was given with weight adjusted intravenous propofol (2-3 mg/kg) and maintained with Oxygen and air with inhalation desflurane (6%) with MAC of 0.8-1.0 and Bispectral index of 40-60. The data of MEP signals were collected at baseline, after instrumentation, decompression, and closure. The MEP data were correlated using Spearman correlation test and Wilcoxon rank test with minimum alveolar concentration, mean arterial pressure, temperature and bispectral index at different time intervals. P value <0.05 was considered statistically significant.
Results: A total of 37 patients (26 females and 11 males) were included in the study with the mean of 52.46±12.85 years. There was no statistically significant correlation between the variables at different time intervals. Although, a statistically significant negative correlation was observed between bispectral index and latency after decompression (p=0.006). A significant difference was observed in visual analogue scale and Oswestry disability index before and after procedure (p< 0.001).
Conclusion: Anaesthesia with 6% desflurane in 0.8-1.0 MAC does not alter MEP signals in patients undergoing spinal surgery without any complication and with adequate recovery rate from anaesthesia.
Keywords: Anaesthesia, Desflurane, Motor evoked potentials, Propofol

References

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How to Cite this Article: Agarwala MS, Modi HN, Patel DJ Desflurane | as an Effective Anaesthetic Agent for Intra- Operative Neuro-Monitoring in Spine Surgeries| Back Bone: The Spine Journal | April 2023- September 2023; 4(1): 20-23 | https://doi.org/10.13107/bbj.2023.v04i01.055

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